Quick question using SonED2:
Is it possible to import a tileset made in GIMP? If so, how do I make a tileset? As in, what needs to be kept in mind when making Sonic 1 hacks with original tilesets?
If you really mean tiles (8x8), yes, it's possible, but it may be a huge lot of work since tiles are hard to recognize. If you really want to edit the tiles themselves, you should first export the tiles from an existing level (misc > export to image > tiles), then open them in GIMP and edit them. Don't forget you can only use one row of colors per tile (the rows top-left when you're in soned2's tile editor), so editing tiles in GIMP may not be really user-friendly.
I think you should try with blocks instead, the palette problems are a little more complex (1 row of colors per tile, 4 tiles per block), but it's much easier to see what you're doing with those.
Palettes are probably the only problem actually.
Then import with file > import from image > tiles (or blocks). It may take a few seconds (chunks do, don't know about tiles and blocks).